Design, plan, manage and deliver internal and client research projects
Perform in vitro experiments and assays to an exceptional standard
Maintain mammalian cell cultures across a variety of scientific fields and disease settings (e.g. cancer, neuroscience, cardiovascular)
Develop and optimise cell based assays utilising the automation platform
Data analysis, interpretation and presentation (including written reports and presentations) of experiment results
Keeping thorough documentation of work that has been carried out
Following standard operating procedures where required and establishing new SOPs when required
Providing feasibility assessments of projects in advance to aid the sales team
Act as subject matter expert and communicate effectively with clients in scientific meetings
Keeping up to date with relevant scientific and technical development
Work well within a team to optimise processes, teach others and learn
Contribute ideas to technology development strategies and maintain a culture of continual improvement
Ideally educated to PhD level in cell biology or related fields; equivalent experience in scientific R&D
2+ years of postdoctoral or industrial drug discovery experience
Experience of independent, self-directed work
Proven ability to disseminate research results e.g. in reports, presentations and peer reviewed journal publications
Assay development expertise for target ID/validation and/or drug screening, with a good understanding of assay statistics (e.g. Robust Z’, %CV).
Broad understanding of the drug discovery process
Experience handling large datasets including data QC and analysis
Experience of working in an industrial setting
Broad-based experience in cell biology, ideally including:
Mammalian cell culture and complex cell models (such as 3D cell models, iPSC or other primary cell systems or co-cultures) including development/optimization of culturing conditions.
Implementing, performing and troubleshooting a broad range of cell based assays (for example: flow cytometry, imaging microscopy or plate-based assays (such as NanoBRET, HiBiT, ELISA, Luciferase, HTRF and AlphaLISA).
Practical experience with one or more gene engineering and gene modulation technologies (e.g. CRISPR or RNAi mediated gene modulation) for cell line engineering/development or genetic perturbation studies.
Expertise in a wide range of other common cellular and molecular techniques, including qRT-PCR, transfection, SDS-PAGE, Western Blotting,
In addition (desired, but not required):
Expertise in neurodegenerative diseases, immunology, oncology and/or immuno-oncology, together with demonstrated experience in complementary advanced techniques including primary cell cultures and 3D cell models
Proficiency in any advanced cellular and molecular biology techniques (e.g. multiparameter flow cytometry or high throughput/high content imaging and the associated analysis.
Experience and knowledge of research processes and activities and requirements to comply with Human Tissue Act
Experience in the use, programming and troubleshooting of robotic liquid handlers.
Experience in executing assays using an automated platform
Experience in programming the Hamilton-Vantage liquid handler using the Instinct V software.
Experience in programming robotic arms and integrating equipment onto automation platforms.
Experience in automating complex scientific processes (ideally cell-based assays), including troubleshooting and method validation..
Basic programming skills, ideally in either Python or C# (not crucial which language - but ability to learn new is very good).
Experience in setting up and/or running high throughput screening (HTS) assays
Culture
Dedicated, passionate and agile team who are constantly innovating and learning
Flexible and collaborative work culture with extensive development and progression opportunities
Inclusion, diversity and belonging is core to our success. We embrace everything unique and continue to be proud of our diverse, rich culture. When you are at your best, we are at our best
Benefits
Highly competitive reward package
Pension scheme, Life and illness insurance cover and other benefits, including salary sacrifice schemes such as Tusker cars, Nursery cover, gym membership and bike to work
Generous company sick pay scheme and enhanced family-friendly policies
Health and well-being support
A minimum of 28 days’ annual leave, together with generous flexible and remote working opportunities to ensure you have a great work/life balance
Regular team events, fresh fruit and snacks and lots of opportunities to socialise and build great relationships
Arctoris is a technology-enabled drug discovery services company headquartered in Oxford. We combine automated wet lab experimentation, proprietary analytical pipelines, and deep scientific expertise to accelerate the design and optimisation of new therapeutics. Our proprietary Ulysses® automation platform and data infrastructure enable the generation of reproducible, high-quality datasets at scale, forming the foundation for AI-driven discovery capabilities across oncology, immunology, and neurodegeneration.
We operate at the intersection of biology, robotics, and data science, building systems that transform how scientists generate and interpret experimental data. Joining Arctoris means contributing to a multidisciplinary environment where innovation in data architecture, analytical tooling, and computational pipelines directly advances the creation of life-changing medicines.